QUANTIFICATION OF ANGIOGENESIS ON THE RAT AORTIC RING ASSAY
نویسندگان
چکیده
منابع مشابه
Quantification of Angiogenesis on the Rat Aortic Ring Assay
Image analysis is used to quantify angiogenesis on the rat aortic ring model. This technique allows to determine: (1) the aortic ring area and factor shape; (2) the number of microvessels, the total number of branching, the maximal microvessel length and the number of microvessels in function of the distance to the aortic ring; (3) the total number of isolated fibroblast-like cells and the numb...
متن کاملHoney promotes angiogeneic activity in the rat aortic ring assay.
OBJECTIVE To investigate possible effects of honey on angiogenesis, using in vitro analogues of angiogenesis and an endothelial proliferation assay. METHOD Using an in vitro rat aortic ring assay we compared pseudotubule formation by medicinal honey (Activon), supermarket honey (Rowse) and a honey-based ointment (Mesitran), with that of artificial honey (70% w/w sugar glucose/fructose). Pseud...
متن کاملInhibitory effect of curcumin on angiogenesis in a streptozotocin-induced diabetic rat model: An aortic ring assay
BACKGROUND Curcumin (diferuloylmethane) has been associated with the inhibition of angiogenesis, as well as the prevention of cancers and inflammatory processes. The aim of this study was to assess the efficacy of curcumin in suppressing angiogenesis in the cultured endothelial cells of rat aortic rings. METHODS Eight-week-old male Wistar rats were randomized into five groups each with a diff...
متن کاملAortic Ring Assay
Angiogenesis, the sprouting of blood vessels from preexisting vasculature is associated with both natural and pathological processes. Various angiogenesis assays involve the study of individual endothelial cells in culture conditions (1). The aortic ring assay is an angiogenesis model that is based on organ culture. In this assay, angiogenic vessels grow from a segment of the aorta (modified fr...
متن کاملRat Mesentery Angiogenesis Assay
The adult rat mesentery window angiogenesis assay is biologically appropriate and is exceptionally well suited to the study of sprouting angiogenesis in vivo [see review papers], which is the dominating form of angiogenesis in human tumors and non-tumor tissues, as discussed in invited review papers(1,2). Angiogenesis induced in the membranous mesenteric parts by intraperitoneal (i.p.) injectio...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Image Analysis & Stereology
سال: 2011
ISSN: 1854-5165,1580-3139
DOI: 10.5566/ias.v22.p43-48